Immunohistochemistry
Immunohistochemistry with Lung tissue at an antibody concentration of 5ug/ml using anti-PTPN11 antibody| Product Name | Rabbit anti-PTPN11 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BPTP3, CFC, MGC14433, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2 |
| Immunogen | The immunogen for anti-PTPN11 antibody: synthetic peptide directed towards the N terminal of human PTPN11 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMousePigRabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTPN11 |
|---|---|
| Gene Synonyms | BPTP3 CFC MGC14433 NS1 PTP-1D PTP2C SH-PTP2 SH-PTP3 SHP2 |
| Gene Full Name | Protein tyrosine phosphatase, non-receptor type 11 |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. |
| Alternative Names | BPTP3 CFC MGC14433 NS1 PTP-1D PTP2C SH-PTP2 SH-PTP3 SHP2 |
| Molecular Weight(MW) | 68kDa |
| Sequence | 593 amino acids |
Immunohistochemistry
Immunohistochemistry with Lung tissue at an antibody concentration of 5ug/ml using anti-PTPN11 antibody| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM116658