Application
Western blot analysis of anti-ADAMTS5 Antibody (Center) in mouse muscle tissue lysates (35ug/lane). ADAMTS5(arrow) was detected using the purified Pab.| Product Name | ADAMTS5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADAMTS5; ADAMTS11; ADMP2; A disintegrin and metalloproteinase with thrombospondin motifs 5; A disintegrin and metalloproteinase with thrombospondin motifs 11; ADMP-2; Aggrecanase-2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ADAMTS11 ADMP2 |
|---|---|
| Alternative Names | ADAMTS5 ADAMTS11 ADMP2 A disintegrin and metalloproteinase with thrombospondin motifs 5 A disintegrin and metalloproteinase with thrombospondin motifs 11 ADMP-2 Aggrecanase-2 |
| Molecular Weight(MW) | 101718 Da |
| Function | Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period |
| Tissue Specificity | Expressed at low level in placenta primarily but also detected in heart and brain, cervix, uterus, bladder, esophagus, rib cartilage, chondroblastoma, fibrous tissue and a joint capsule from an arthritic patient |
| Cellular Localization | Secreted, extracellular space, extracellular matrix (By similarity) |
| Entrez Gene | 11096 |
|---|
Application
Western blot analysis of anti-ADAMTS5 Antibody (Center) in mouse muscle tissue lysates (35ug/lane). ADAMTS5(arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Data sheet for OM225886