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ISL1 Antibody
Catalog Number:OM282365
OM282365
Discount Price
OM282365-100ul
1~2 Week
100ul
OM282365-50ul
50ul
OM282365-20ul
20ul
1~2 Week
Product Profile
Product Name ISL1 Antibody
Antibody Type Primary Antibodies
Product description ISL1 is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. ISL1 is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. Please see the Entrez Gene record to access additional publications.1) Laurin, N., (er) Am. J. Med. Genet. B Neuropsychiatr. Genet. (2008) In press.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ISL1.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAWB
ISL1 antibody can be used for detection of ISL1 by ELISA at 1:312500. ISL1 antibody can be used for detection of ISL1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ISL1
Alternative Names ISL1
Isl-1
ISLET1
Molecular Weight(MW) 39 kDa
Database Links
Entrez Gene 3670
Protein Accession NP_002193
Application

Application

Antibody used in WB on Human Muscle at 0.2-1 ug/ml.
Positive Control 1) Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Application Notes ISL1 antibody can be used for detection of ISL1 by ELISA at 1:312500. ISL1 antibody can be used for detection of ISL1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store ISL1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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