This gene encodes a protein that is related to
chondromodulin-I, which is a cartilage-specific glycoprotein that
functions to stimulate chondrocyte growth and to inhibit tube
formation of endothelial cells. This protein is also an
angiogenesis inhibitor. Genetic variation in this gene is
associated with a risk for type 2 diabetes, central obesity and
serum levels of systemic immune mediators in a body size-dependent
manner. This gene is also a candidate gene for age-related macular
degeneration, though a direct link has yet to be demonstrated.1) Saiki, A., et al. J. Clin. Endocrinol. Metab. 94(10):3987-3994(2009)
Immunogen
This TNMD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-241 amino acids from the Central region of human TNMD.
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Application
Western blot analysis in mouse kidney tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.