This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants.
Molecular Weight(MW)
86 kDa
Cellular Localization
Cytoplasm
Application
WB
Western blot analysis using PFKP antibody against Jurkat(1), THP-1(2),A461(3),HUVEC(4) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded lung cancer tissues using PFKP antibody with DAB staining.
Application Notes
WB:1:200-1:2000 IHC:1:200-1:1000
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.