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Cleaved PARP1 Rabbit mAb
Catalog Number:OM643965
OM643965
Discount Price
OM643965-100ul
100ul
OM643965-50ul
50ul
OM643965-20ul
20ul
Product Profile
Product Name Cleaved PARP1 Rabbit mAb
Antibody Type Primary Antibodies
Key Feature
Clonality monoclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
WB:1:500-1:5000
IHC:1:200-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol PARP1
Gene Synonyms PARP
PARS
PPOL
ADPRT
ARTD1
ADPRT1
PARP-1
ADPRT 1
pADPRT-1
Poly-PARP
Gene Full Name poly(ADP-ribose) polymerase 1
Gene Summary This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 25kDa
Cellular Localization Cytoplasmic, Nuclear.
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Cleaved PARP1 antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: RAW264.7 Lane 2: Hela Predicted band size: 25kDa.

IHC

Rat colon tissue was stained with Anti-Cleaved PARP1 rabbit Antibody.

IHC

Human tonsil tissue was stained with Anti-Cleaved PARP1 rabbit Antibody.
Application Notes WB:1:500-1:5000
IHC:1:200-1:1000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year(Do not lower than -25°C)
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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