Western blot
Titration: 1.0 ug/mlPositive Control: HepG2 Whole Cell| Product Name | Rabbit anti-NR3C1 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GCCR, GCR, GR, GRL |
| Immunogen | The immunogen for anti-NR3C1 antibody: synthetic peptide directed towards the N terminal of human NR3C1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NR3C1 |
|---|---|
| Gene Synonyms | GCCR GCR GR GRL |
| Gene Full Name | Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| Gene Summary | NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. |
| Alternative Names | GCCR GCR GR GRL |
| Molecular Weight(MW) | 86kDa |
| Sequence | 777 amino acids |
| Entrez Gene | 2908 |
|---|---|
| SwissProt ID | P04150 |
| Protein Accession | NP_001018086 |
Western blot
Titration: 1.0 ug/mlPositive Control: HepG2 Whole Cell| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM105256