Application
CD86 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the CD86 antibody detected the CD86 protein (arrow).| Product Name | CD86 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD_antigen=CD86; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD28LG2 |
|---|---|
| Alternative Names | CD86 CD28LG2 T-lymphocyte activation antigen CD86 Activation B7-2 antigen B70 BU63 CTLA-4 counter-receptor B7.2 FUN-1 CD_antigen=CD86 Flags: Precursor |
| Molecular Weight(MW) | 37682 Da |
| Function | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T- cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation |
| Tissue Specificity | Expressed by activated B-lymphocytes and monocytes |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Entrez Gene | 942 |
|---|---|
| Nucleotide Accession | NP_008820.2 NP_787058.3 |
Application
CD86 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the CD86 antibody detected the CD86 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Data sheet for OM229299