ADRB2, beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This protein is intronless.1) Kobilka B.K., Dixon R.A.F.Proc. Natl. Acad. Sci. U.S.A. 84:46-50(1987)
Immunogen
This ADRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from human ADRB2.
Western blot analysis of anti-ADRB2 Antibody (T384) in SK-BR-3 cell line lysates (35ug/lane)
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.