Application
Immunohistochemistry staining of AKR1B10 in colon tissue using AKR1B10 Antibody.| Product Name | AKR1B10 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AKR1B10, AKR1B11, Aldose reductase-like peptide, ALDRLn, AKR1B12, Aldose reductase-like, Aldose reductase-like 1, ARP, HARP, HSI, Small intestine reductase, ARL-1, SI reductase |
| Product description | ARK1B10, a 316A.A protein, catalyzes efficient reduction ofaliphatic and aromatic aldehydes. It the first cytosolic NADP (H)-dependent retinal reductase described in humans and is characterized by the presence of a novel NADP binding motif. Due to its ability to convert glucose to sorbitol, AKR1B10 may have a role in development of secondary diabetic complications.It is abundantly expressed in adrenal gland, small intestine and colon, with lower levels in liver, thymus, prostate, testis, and skeletal muscle and its levels are up regulated in certain cancers such as hepatocellular carcinoma. |
| Immunogen | A portion of amino acids 100-200 of human AKR1B10 protein. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| AKR1B10 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | AKR1B10 |
|---|---|
| Alternative Names | AKR1B10 AKR1B11 Aldose reductase-like peptide ALDRLn AKR1B12 Aldose reductase-like Aldose reductase-like 1 ARP HARP HSI Small intestine reductase ARL-1 SI reductase |
| Tissue Specificity | The NCBI accession number for AKR1B10 is EAL24068. |
Application
Immunohistochemistry staining of AKR1B10 in colon tissue using AKR1B10 Antibody.| Application Notes | AKR1B10 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store AKR1B10 antibody at 4 ˚C for short term applications. For long term storage, aliquot and -20 ˚C. |
| Storage Buffer | PBS, 0.2% gelatin, 0.05% sodium azide. |
Data sheet for OM270665