Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMK2A (C-term E370) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.Application
Western blot analysis of CAMK2A using rabbit polyclonal C using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CAMK2A gene (Lane 2).Application
Western blot analysis of anti-C in 293 cell line lysates (35ug/lane).| Product Name | CAMK2A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CAMK2A belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by the gene for CAMK2A is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity.1) Lee,C.W., Mol. Pharmacol. 73 (5), 1454-1464 (2008) |
| Immunogen | This CAMK2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-371 amino acids from the C-terminal region of human CAMK2A. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | CAMK2A |
|---|---|
| Alternative Names | Calcium/calmodulin-dependent protein kinase type II subunit alpha CaM kinase II subunit alpha CaMK-II subunit alpha CAMK2A CAMKA KIAA0968 |
| Molecular Weight(MW) | 54 kDa |
Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMK2A (C-term E370) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Application
Western blot analysis of CAMK2A using rabbit polyclonal C using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CAMK2A gene (Lane 2).
Application
Western blot analysis of anti-C in 293 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
Data sheet for OM273341