Application
Western blot analysis of extracts from cos-7 cells (Lane 2), using Caveolin 2 (Phospho-Tyr27) Antibody. The lane on the left is treated with antigen-specific peptide.| Product Name | Caveolin 2 (phospho Tyr27) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CAV2, Caveolin-2 |
| Product description | The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.1) Scherer P.E., Proc. Natl. Acad. Sci. U.S.A. 93:131-135(1996). |
| Immunogen | Caveolin 2 (phospho Tyr27) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 27 (L-E-Y (p)-A-D) derived from Human Caveolin 2. |
| Modification | Phosphoralated |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CAV2 |
|---|---|
| Alternative Names | CAV2 Caveolin-2 |
| Molecular Weight(MW) | 26 kDa |
| Tissue Specificity | The antibody detects endogenous levels of Caveolin 2 only when phosphorylated at tyrosine 27. |
| Entrez Gene | 858 |
|---|---|
| Protein Accession | NP_001224.1 |
Application
Western blot analysis of extracts from cos-7 cells (Lane 2), using Caveolin 2 (Phospho-Tyr27) Antibody. The lane on the left is treated with antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM273569