Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.1) Kutateladze T. G., Ogburn K. D., Watson W. T., de Beer T., Emr S. D., Burd C. G., Overduin M. Mol. Cell 3:805-811 (1999) Merithew E., Stone C., Eathiraj S., Lambright D. G. J. Biol. Chem. 278:8494-8500 (2003) Dumas J. J., Merithew E., Sudharshan E., ajamani D., Hayes S., Lawe D., Corvera S., Mol. Cell 8:947-958 (2001)
Immunogen
EEA1 antibody was raised against a peptide sequence around aa.12~16 (R-V-G-S-Q) derived from Human EEA1.