PDZ and LIM domain protein 3, Actinin-associated LIM protein, Alpha-actinin-2-associated LIM protein, PDLIM3, ALP
Product description
The protein encoded by this gene contains a PDZ domain and
a LIM domain, indicating that it may be involved in cytoskeletal
assembly. In support of this, the encoded protein has been shown to
bind the spectrin-like repeats of alpha-actinin-2 and to colocalize
with alpha-actinin-2 at the Z lines of skeletal muscle. This gene
is found near a region of chromosome 4 that has been implicated in
facioscapulohumeral muscular dystrophy, but this gene does not
appear to be involved in the disease. Two transcript variants
encoding different isoforms have been found for this gene.1) Hershberger, R.E., et al. Clin Transl Sci 1(1):21-26(2008)
Immunogen
This PDLIM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-355 amino acids from the C-terminal region of human PDLIM3.
Western blot analysis in HL-60 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.