This gene encodes a trypsinogen, which is a member of the
trypsin family of serine proteases. This enzyme is highly expressed
in prostate epithelia and is one of several proteolytic enzymes
found in seminal fluid. The proprotein is cleaved to produce a
light chain and a heavy chain which are associated by a disulfide
bond. It is active on peptide linkages involving the carboxyl group
of lysine or arginine.1) Chen, Y.W., et al. J. Biol. Chem. 285(41):31755-31762(2010)
Immunogen
This PRSS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of human PRSS8.
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.