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Angiopoietin 1 (ANGPT1) Goat Polyclonal Antibody
Catalog Number:OM643969
Human
WB
OM643969
Discount Price
OM643969-100ul
100ul
Product Profile
Product Name Angiopoietin 1 (ANGPT1) Goat Polyclonal Antibody
Antibody Type Primary Antibodies
Immunogen Peptide with sequence C-PDFSSQKLQH, from the internal region of the protein sequence according to NP_001137.2.
Key Feature
Clonality polyclonal
Isotype IgG
Host Species Goat
Tested Applications WB
WB:1-2ug/ml
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ANGPT1
Gene Synonyms AGP1
AGPT
ANG1
HAE5
AGPT-1
Gene Full Name angiopoietin 1
Gene Summary This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Mutations in this gene are associated with hereditary angioedema. [provided by RefSeq, Aug 2020]
Molecular Weight(MW) 50kDa
Cellular Localization Secreted.
Application

WB

HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human ANGPT1 with DDK (FLAG) tag probed with ANGPT1 antibody (1ug/ml) in Lane A and probed with anti-DDK Tag (1:1000,in Lane C. Mock-transfected HEK293 probed with ANGPT1 antibody (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence..
Application Notes WB:1-2ug/ml
Additional Information
Form Liquid
Storage Instructions Store at -20°C as received.
Storage Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
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