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Glutathione Reductase Rabbit Polyclonal Antibody
Catalog Number:OM644176
OM644176
Discount Price
OM644176-20ul
20ul
OM644176-50ul
50ul
OM644176-100μl
2~3 Week
100μl
Product Profile
Product Name Glutathione Reductase Rabbit Polyclonal Antibody
Antibody Type Primary Antibodies
Immunogen Recombinant protein within Human GLUR aa 273-446 / 522.
Key Feature
Clonality polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications FCICC/IFIHCWB
WB:1:1000-1:2000
IHC:1:50-1:200
ICC/IF:1:50-1:200
FC:1:50-1:100
Species Reactivity HumanRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol GSR
Gene Synonyms GR
GSRD
HEL-75
CNSHA10
HEL-S-122m
Gene Full Name glutathione-disulfide reductase
Gene Summary This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010]
Molecular Weight(MW) 56 KDa
Cellular Localization Cytoplasm. Mitochondrion.
Application

WB

Western blot analysis of GLUR on different lysates using anti-GLUR antibody at 1/2,000 dilution. Positive control: Lane 1: A549, Lane 2: Rat liver tissue.

IHC

Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-GLUR antibody. Counter stained with hematoxylin.

IHC

Immunohistochemical analysis of paraffin-embedded human thyroid gland tissue using anti-GLUR antibody. Counter stained with hematoxylin.

ICC/IF

ICC staining GLUR in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

FC

Flow cytometric analysis of A549 cells with GLUR antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application Notes WB:1:1000-1:2000
IHC:1:50-1:200
ICC/IF:1:50-1:200
FC:1:50-1:100
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
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