WB
Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-LRP6 antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Hela, Lane 2: Jurkat, Lane 3: HEK293.IHC
Human brain was stained with anti-LRP6 rabbit antibody.IHC
Rat brain was stained with anti-LRP6 rabbit antibody.| Product Name | LRP6 Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:2000-1:10000 IHC:1:200-1:1000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | LRP6 |
|---|---|
| Gene Synonyms | ADCAD2 STHAG7 |
| Gene Full Name | LDL receptor related protein 6 |
| Gene Summary | This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009] |
| Molecular Weight(MW) | 180kDa(Calculated),210kDa(Observed). |
| Cellular Localization | Membrane. |
WB
Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-LRP6 antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Hela, Lane 2: Jurkat, Lane 3: HEK293.
IHC
Human brain was stained with anti-LRP6 rabbit antibody.
IHC
Rat brain was stained with anti-LRP6 rabbit antibody.| Application Notes | WB:1:2000-1:10000 IHC:1:200-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
Data sheet for OM644224