Application
Western blot analysis of WHSC1L1 (arrow) using rabbit polyclonal WHSC1L1 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the WHSC1L1 gene.| Product Name | WHSC1L1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | WHSC1L1; NSD3; Histone-lysine N-methyltransferase NSD3; Nuclear SET domain-containing protein 3; Protein whistle; WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; Wolf-Hirschhorn syndrome candidate 1-like protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NSD3 |
|---|---|
| Alternative Names | WHSC1L1 NSD3 Histone-lysine N-methyltransferase NSD3 Nuclear SET domain-containing protein 3 Protein whistle WHSC1-like 1 isoform 9 with methyltransferase activity to lysine Wolf-Hirschhorn syndrome candidate 1-like protein 1 |
| Molecular Weight(MW) | 161613 Da |
| Function | Histone methyltransferase. Preferentially methylates 'Lys-4' and 'Lys-27' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression |
| Tissue Specificity | Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung |
| Cellular Localization | Nucleus (By similarity). Chromosome (By similarity) |
| Entrez Gene | 54904 |
|---|---|
| Nucleotide Accession | NP_060248.2 NP_075447.1 |
Application
Western blot analysis of WHSC1L1 (arrow) using rabbit polyclonal WHSC1L1 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the WHSC1L1 gene.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Data sheet for OM224698