Application
A. Immunohistochemical analysis of paraffin-embedded human urinary bladder using anti-Caveolin-1 RabMAb (Cat. #AJ1140a).Application
B. Immunohistochemical analysis of paraffin-embedded human lungs using anti-Caveolin-1 RabMAb (Cat. #AJ1140a).Application
C. Western blot analysis on A431 cell lysate using anti-Caveolin-1 RabMAb (Cat. #AJ1140a); dilution 1:20,000.| Product Name | Caveolin-1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | E249 |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:250 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CAV |
|---|---|
| Alternative Names | CAV1 CAV Caveolin-1 |
| Molecular Weight(MW) | 20472 Da |
| Function | May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway |
| Tissue Specificity | Expressed in muscle and lung, less so in liver, brain and kidney |
| Cellular Localization | Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein Membrane, caveola; Peripheral membrane protein. Membrane raft Note=Colocalized with DPP4 in membrane rafts. Potential hairpin- like structure in the membrane. Membrane protein of caveolae |
| Entrez Gene | 857 |
|---|
Application
A. Immunohistochemical analysis of paraffin-embedded human urinary bladder using anti-Caveolin-1 RabMAb (Cat. #AJ1140a).
Application
B. Immunohistochemical analysis of paraffin-embedded human lungs using anti-Caveolin-1 RabMAb (Cat. #AJ1140a).
Application
C. Western blot analysis on A431 cell lysate using anti-Caveolin-1 RabMAb (Cat. #AJ1140a); dilution 1:20,000.| Application Notes | IHC:1:250 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
Data sheet for OM228808