Application
Application| Product Name | E6AP antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antiserum to E6APThe E6-associated protein (E6-AP/UBE3A), a 100a protein, was originally identified as an ubiquitin-protein ligase (E3), in the presence of the E6 protein from human papillomavirus types 16 and 18. E6-AP has also been shown to function as a coactivator of steroid receptor-dependent transcriptional activity. Recent data indicate that the ubiquitin-protein ligase function of E6-AP is dispensable for its ability to coactivate nuclear hormone receptors, showing that E6-AP possesses two separable independent functions, as both a coactivator and a ubiquitin-protein ligase. |
| Immunogen | Recombinant protein encoding amino acids residues 1-851 of human E6-AP expressed in E. coli. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| Optimal dilutions/concentations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | EPVE6AP AS 105830 E6AP ANCR HPVE6A 7337 Q05086 E6-AP UBE3A E6 AP |
|---|---|
| Target | E6AP |
Application
Application| Positive Control | HeLa |
|---|---|
| Application Notes | Optimal dilutions/concentations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM250812