| Product Name | CD11c Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD11C, SLEB6, ITGAX |
| Product description | The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin alpha chain also known as integrin alpha X. It is expressed on macrophages, granulocytes, monocytes, dendritic cells, natural killer cells, and subsets of B and T lymphocytes. The CD11c/CD18 complex associates with the iC3b, fibrinogen and ICAM-1 and has an important function in leukocyte adhesion.1) Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | FACSFunctionalStudiesIFIP |
| FACS:1:200~1:500 IF:1:200~1:500 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ITGAX |
|---|---|
| Alternative Names | CD11C SLEB6 ITGAX |
| Tissue Specificity | The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin alpha chain also known as integrin alpha X. |
| Entrez Gene | 3687 |
|---|
| Application Notes | FACS:1:200~1:500 IF:1:200~1:500 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze. |
| Storage Buffer | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
Data sheet for OM273964