Application
Immunohistochemistry staining of Integrin alpha X in colon, neutrophils tissue using Integrin alpha X Antibody.| Product Name | Integrin alpha X Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ITGAX, CD11c antigen, Integrin alpha-X, Leu M5, alpha subunit, p150 95 integrin alpha chain, SLEB6, CD11C, Leu M5 |
| Product description | ITGAX encodes the integrin alpha X chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 seems to broadly overlap the properties of the alpha M beta 2 integrin in adherence of neutrophils and monocytes to stimulated endothelium, and the phagocytosis of complement coated particles. |
| Immunogen | Integrin alpha X antibody was raised against a peptide located near the internal domain of Integrin alpha X (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| Integrin alpha X antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunoprecipitation: |
|
| Species Reactivity | GorillaHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ITGAX |
|---|---|
| Alternative Names | ITGAX CD11c antigen Integrin alpha-X Leu M5 alpha subunit p150 95 integrin alpha chain SLEB6 CD11C Leu M5 |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TDO2 (57%). |
Application
Immunohistochemistry staining of Integrin alpha X in colon, neutrophils tissue using Integrin alpha X Antibody.| Application Notes | Integrin alpha X antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunoprecipitation: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Integrin alpha X antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
Data sheet for OM282214