Application
Western blot analysis of extract from MCF-7 and HT29 cells using E-Cadherin (CD324).| Product Name | E Cadherin (CD324) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UVO, CDHE, ECAD, LCAM, Arc-1, CD324, CDH1, UVO |
| Product description | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.1) Baki L. et. al (2001) Proc. Natl. Acad. Sci. U. S. A. 98:2381-2386Makagiansar I. T. et. al (2002) J. Biol. Chem. 277:16002-16010Agiostratidou G. (2006) J. Neurochem. 96:1182-1188 |
| Immunogen | E-Cadherin (CD324) antibody was raised against a peptide sequence around aa.864~868 (E-W-G-N-R) derived from Human E-Cadherin. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CDH1 |
|---|---|
| Alternative Names | UVO CDHE ECAD LCAM Arc-1 CD324 CDH1 UVO |
| Molecular Weight(MW) | 135 kDa |
| Tissue Specificity | This antibody detects endogenous level of total E-Cadherin protein. |
| Entrez Gene | 999 |
|---|---|
| Protein Accession | NP_004351.1 |
Application
Western blot analysis of extract from MCF-7 and HT29 cells using E-Cadherin (CD324).| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM277499