| Product Name | FGF-23 Antibody [FG322-3] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | FGF-23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC). |
| Immunogen | Recombinant human FGF-23. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | ELISAIHCWB |
| WB:1:500~1:2000 IHC:1:50~1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FGF23 |
|---|---|
| Alternative Names | Fibroblast Growth Factor 23 Tumor-derived Hypophosphatemia-inducing Factor |
| Tissue Specificity | Recognizes human FGF-23. Does not cross-react with mouse FGF-23. |
| Entrez Gene | 8074 |
|---|---|
| Protein Accession | NP_065689.1 |
| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 1 year after receipt when stored at -20˚C. |
| Storage Buffer | Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives. |
Data sheet for OM278777